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Evolution of extracellular matrix biology of extracellular matrix kindle edition by fred w keeley robert mecham download it once and read it on your kindle device pc phones or tablets use features like bookmarks note taking and highlighting while reading evolution of extracellular matrix biology of extracellular matrix. The evolution of single cells into multicellular organisms was mediated in large part by the extracellular matrix the proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes facilitate cell adhesion and migration and impart mechanical properties that are important for tissue function. Dr robert mecham is the alumni endowed professor of cell biology and physiology at washington university school of medicine he holds joint appointments at the professorial level in medicine pediatrics and bioengineering he received his bachelor of science degree in biology at the university of utah in 1973 where he developed an interest in the extracellular matrix proteins that contribute . Volume the extracellular matrix an overview robert p mecham editor is the first under the new publisher it should also be noted that the series is being. Regulated turnover of extracellular matrix ecm is an important component of tissue homeostasis in recent years the enzymes that participate in and control ecm turnover have been the focus of research that touches on development tissue remodeling inflammation and disease